P-221: Toxoplasmosis and Female Infertility

Background: Toxoplasma gondii is an obligate intracellular parasite, which affects a wide-range of mammals including human. Based on serological studies, T. gondii is one of the most prevalent protozoan parasites. Most cases of toxoplasmosis are asymptomatic or mild and influenza-like, but immunocompromised patients often develop fulminating life-threatening symptoms as pneumonia and encephalitis. Recently recorded a relation between female infertility and toxoplasmosis in China, which raises the concern about the importance of toxoplasmosis in female fertility problems. Materials and Methods: This study reviews the use of internal and external sources and is made available on the Internet Results: It is well documented that toxoplasmosis is of crucial importance owing to cosmopolitan distribution and wide range of diseases which cause. It is known that toxoplasmosis has some unfavorable effects on the reproductive capacity of both men and women. The overall detection rate of toxoplasmosis among Egyptian females in childbearing age was 57.52%, distribution especially in the third world countries easier and cheaper to be carried out particularly in the time of high incidence of the disease. However, it was shown that the high number of toxoplasmosis cases were recorded among females seen among families with one baby being already delivered the seroprevalence of T. gondii IgG and IgM among nonpregnant women was higher than pregnant group.In contrast, pregnant women were mostly under risk of catching toxoplasmosis as concluded elsewhere. However, T. gondii infection in human may occur vertically that are passed to the foetus via the placenta, or horizontal transmission which may involve three life cycle stages i.e. the women examined might be already infected with disease before marriage and she might be chronic carrier of the parasite concerned distribution of toxoplasmosis is due to many risk factors including age, number of deliveries, contact with host animals (small ruminants), contact with uncooked meat, drinking raw sheep or goat milk Conclusion: Accordingly, the implementation of health education programs aimed to primary prevention of toxoplasmosis is mandatory. Also, the infertile females had a significant higher prevalence of T. gondii infection than the controls especially in older ages. These data highlight the possible correlation between Toxoplasma infection and infertility